Cystic Fibrosis

Cystic fibrosis (CF) is the most common life-limiting genetic disorder affecting Australians today, for which there is no cure. 1 in every 2,500 babies born have CF and one in 25 Australians carry the gene.

CF research helps us understand how the disease is caused, how it develops and how it can be best treated.

What we are doing now and where our research is taking us

A number of research projects are being carried out by researchers within the Cystic Fibrosis and Bronchiectasis Unit. These include studies investigating the relationship between the gut microbiome and the overall health in adults with CF and how bacterial infections such as Pseudomonas aeruginosa and Clostridium difficile affect CF patients. Allied Health staff are conducting the first studies in adult patients with CF.

PhD Candidates, who are funded by Conquer CF, are investigating the effectiveness high- intensity interval training for CF patients and the effect of the Metaneb® System has when used in conjunction with usual AWC techniques on lung clearance, lung mechanics and airflow limitation during periods of clinical stability and hospitalisation.

Our Clinical Trials Unit also undertakes CF studies to explore new ways to prevent the disease and improve the quality of everyday life for those diagnosed with CF.

Thanks to the support of Conquer CF, we are conducting the first trial into the effects of high-intensity interval training in people with CF.

Abbey Sawyer, Conquer CF PhD Candidate

“I can’t explain how much of a difference I have felt both in terms of my health and in my general quality of life since being a part of the clinical trials.”

Michael, former clinical trials patient